Bandits on Thursday afternoon struck at Federal Government College in Birnin-Yauri in Yelwa-Yauri LGA of Kebbi state and abducted scores of female students and staff.
A policeman who tried to challenge the bandits was gunned down, according to eyewitnesses in the town.
The police in Kebbi confirmed the attack.
The abduction is the latest in a series of school kidnappings that have rocked the country in recent months.
Early in June, no fewer than 88 people were killed by bandits in communities in in Danko-Wasagu Local Government Area the State.
Female students abducted from a Muslim school in Rafi local government area of Niger State early this month are still in captivity.
In late May, about 200 students of an Islamiyya school in Niger state were abducted by gunmen.
Some 14 students and staff of Greenfield University in Kaduna were released in May after parents reportedly paid about N180 million ransom and bought eight motorcycles for the bandits.
The Nigerian Government has denied ever paying ransom to release kidnapped persons and has discouraged the idea.
The government has also repeatedly promised to end the abduction of students across the country.
President Muhammadu Buhari promised the nation that the Kankia Secondary school abduction will be the last in the country. Kankia is less than 50km to his hometown, Daura.
School kidnappings have persisted as the country continues to battle several security challenges, including but not limited to an insurgency in the North-East, banditry in the North-West, secessionist agitations in the South-East and Fulani-Herdsmen crises across the Middle-Belt and several South-West states.